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Will test THR-18 in conjunction with tPA
October 16, 2013
By: Gil Roth
President, Pharma & Biopharma Outsourcing Association
D-Pharm Ltd. has received approval from regulatory authorities in the Ukraine to commence a Phase IIa clinical study of THR-18, to be given with the clot buster drug tissue plasminogen activator (tPA), in patients with acute ischemic stroke. THR-18 is a synthetic therapeutic peptide derived from plasminogen activator inhibitor-1 (PAI-1). This is a double-blind, placebo-controlled, escalating single-dose trial to assess the safety, pharmacokinetics and pharmacodynamics of THR-18 given with tPA t...
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